This article explains what polygenic risk scores (PRS) are and how they are calculated, why they may not work equally well for everyone, and how PRS differs from single-gene…
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Carrying a gene variant doesn't mean you'll get sick. Here's how penetrance works, why two people with the same variant can have completely different outcomes, and what a positive…
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Learn what copy-number changes in DNA are, what they mean for your health, and how genetic testing can identify these variations in plain language.
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Learn how heteroplasmy, the threshold effect, and maternal inheritance shape mitochondrial genetics and disease risk, explained in plain language.
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Learn how reference genome builds hg19 and hg38 differ, why genomic coordinates change between versions, and what it means for your DNA test results.
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A plain language explanation of why estimates of how common a genetic variant is in a population (allele frequency) can differ among gnomAD, ExAC, ALFA, TOPMed, and ClinVar.
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Sequencing kits are HSA and FSA eligible. Learn how to pay with pretax dollars through our new Truemed checkout option and save an average of around 30 percent.
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Artificial intelligence tools are increasingly used to look up medical and genetic information. While AI can be a powerful assistant, it can also produce confident-sounding…
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